Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | TTR | P02766 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CBR1 | P16152 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926565 | 0.87 | TTR (0.42) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL7186092 | 0.74 | TTR (0.75) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL11007647 | 0.72 | MRGPRX4 (0.44) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL10642437 | 0.71 | SLC6A2 (0.46) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL11689776 | 0.70 | SLC6A2 (0.49) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL11689769 | 0.70 | TTR (0.57) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL7663772 | 0.69 | S1PR4 (0.56) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL4015064 | 0.69 | TTR (0.67) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL13236112 | 0.68 | SLC6A2 (0.60) | SLC6A2TTRSLC6A3LMNAMAPT | |
| SCHEMBL8779443 | 0.68 | ALDH1A1 (0.44) | LMNAMAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3193771-A | — | — | None | — | — | JP | disclosed |
| JP-H03193771-A | THIADIAZOLE DERIVATIVE AND PRODUCTION THEREOF | TOSOH CORP | 1991-08-23 | — | — | JP | disclosed |