Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CBR1 | P16152 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755714 | 0.87 | SLC6A2 (0.47) | TTRSLC6A2SLC6A3LMNAMAPT | |
| SCHEMBL10924387 | 0.78 | MEN1 (0.39) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL11064204 | 0.71 | NSD2 (0.39) | LMNAMAPTPGRHSP90AA1HPGD | |
| SCHEMBL7186092 | 0.70 | TTR (0.75) | TTRSLC6A2SLC6A3LMNAMAPT | |
| SCHEMBL11468337 | 0.70 | SLC6A4 (0.33) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL10924094 | 0.69 | KMT2A (0.34) | LMNAHPGDKMT2A | |
| SCHEMBL11623968 | 0.69 | ALDH1A1 (0.43) | LMNAMAPTHPGDMEN1KMT2A | |
| SCHEMBL11007647 | 0.68 | MRGPRX4 (0.44) | TTRSLC6A2SLC6A3LMNAMAPT | |
| SCHEMBL11555180 | 0.68 | P2RX3 (0.35) | MEN1KMT2A | |
| SCHEMBL10642437 | 0.67 | SLC6A2 (0.46) | TTRSLC6A2SLC6A3LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4497807-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-02-05 | — | — | US | disclosed |