Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755721 | 0.87 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1NPSR1NPC1 | |
| SCHEMBL9755720 | 0.84 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9755713 | 0.83 | ALDH1A1 (0.46) | ALDH1A1NPSR1SMN1; SMN2LMNAGAA | |
| SCHEMBL9755706 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28942009 | 0.78 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1NPSR1NPC1 | |
| SCHEMBL28114919 | 0.77 | ALDH1A1 (0.41) | KMT2AALDH1A1NPSR1NPC1MAPT | |
| SCHEMBL7079697 | 0.77 | SMN1; SMN2 (0.53) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL10324404 | 0.76 | SMN1; SMN2 (0.63) | MEN1KMT2AALDH1A1NPSR1NPC1 | |
| SCHEMBL10324405 | 0.76 | SMN1; SMN2 (0.63) | MEN1KMT2AALDH1A1NPSR1NPC1 | |
| SCHEMBL12102109 | 0.72 | KMT2A (0.53) | MEN1KMT2AALDH1A1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991006533-A1 | NOVEL PROCESS FOR MANUFACTURING COMPOUNDS WITH VALUABLE PHARMACOLOGICAL PROPERTIES AND NEW INTERMEDIATE PRODUCTS FOR THE MANUFACTURE OF THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1991-05-16 | — | — | WO | disclosed |