3-Methylbutanoic Acid

3-Methylbutanoic Acid

SCHEMBL9755747

CC(=O)C(=O)O.CC(C)CC(=O)O.CCC(C)C(=O)CC(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CACNA2D1 P54289 2/20 0.32
CACNB3 P54284 1/20 0.32
CACNA1C Q13936 1/20 0.32
PGR P06401 1/20 0.32
ADRA1A P35348 1/20 0.32
HTR2B P41595 1/20 0.32
CACNA2D2 Q9NY47 1/20 0.32
KISS1R Q969F8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL518088 0.82 LDHA (0.40) ALDH1A1TDP1
3-Methylbutanoic Acid SCHEMBL28545967 0.80 TDP1 (0.52) ALDH1A1TDP1CACNA2D1CACNB3CACNA1C
SCHEMBL9126999 0.75 SLC22A6 (0.33) TDP1CACNA2D1CACNB3CACNA1CPGR
3-Methylbutanoic Acid SCHEMBL6240548 0.74 CYP1A2 (0.44) ALDH1A1TDP1CACNA2D1CACNB3CACNA1C
3-Methylbutanoic Acid SCHEMBL3670028 0.73 FFAR3 (0.54) ALDH1A1TDP1
SCHEMBL6914535 0.72 LDHA (0.35) ALDH1A1TDP1
SCHEMBL7948515 0.72 ALDH1A1 (0.39) ALDH1A1TDP1
SCHEMBL268814 0.71 ALDH1A1 (0.46) ALDH1A1TDP1
3-Methylbutanoic Acid SCHEMBL9170064 0.71 CYP1A2 (0.41) ALDH1A1TDP1CACNA2D1CACNB3CACNA1C
3-Methylbutanoic Acid SCHEMBL609818 0.71 TDP1 (0.58) ALDH1A1TDP1CACNA2D1CACNB3CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0408674-A1 ALTERNATIVE ENERGY SUBSTRATE Kabi Pharmacia AB (SE) 1991-01-23 EP claimed
WO-1990002726-A1 ALTERNATIVE ENERGY SUBSTRATE KABIVITRUM AB (SE) 1990-03-22 WO claimed