Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8902587 | 0.92 | KDM4E (0.34) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL8902819 | 0.92 | KDM4E (0.34) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL8902600 | 0.88 | ALDH1A1 (0.35) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8902842 | 0.88 | ALDH1A1 (0.35) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL9520715 | 0.83 | KDM4E (0.33) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL9521041 | 0.83 | KDM4E (0.33) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL9755783 | 0.82 | HTT (0.36) | KDM4ENPC1RAB9AALDH1A1MAPT | |
| SCHEMBL8902595 | 0.82 | CTH (0.36) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL8902823 | 0.82 | IDO1 (0.39) | ADORA3ADORA2AADORA1KDM4ENPC1 | |
| SCHEMBL8902603 | 0.80 | AKT1 (0.36) | ADORA3ADORA2AADORA1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019725-A2 | HETEROCYCLIC ANTHRACYCLIONE AND ANTHRACYCLINE ANALOGS | BIOCHEM PHARMA INC. (CA) | 1991-12-26 | — | — | WO | disclosed |