Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | MAOA | P21397 | 5/20 | 0.53 |
| ▸ | DAPK1 | P53355 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13154692 | 0.84 | MAOA (0.63) | MEN1KMT2AMAPTMAOAHPGD | |
| SCHEMBL11134072 | 0.82 | MAPT (0.47) | MEN1KMT2AMAPTMAOADAPK1 | |
| SCHEMBL899150 | 0.80 | MEN1 (0.68) | MEN1KMT2AMAPTMAOADAPK1 | |
| SCHEMBL13452113 | 0.80 | MAOA (0.41) | MEN1KMT2AMAPTMAOADAPK1 | |
| SCHEMBL31745135 | 0.78 | MAPT (0.44) | MEN1KMT2AMAPTMAOADAPK1 | |
| SCHEMBL11291057 | 0.78 | MAPT (0.44) | MEN1KMT2AMAPTMAOADAPK1 | |
| SCHEMBL10113945 | 0.78 | EGFR (0.64) | MEN1KMT2AMAPTMAOAALDH1A1 | |
| SCHEMBL8581315 | 0.76 | MEN1 (0.63) | MEN1KMT2AMAPTMAOADAPK1 | |
| SCHEMBL11490030 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AMAPTMAOAALDH1A1 | |
| SCHEMBL497005 | 0.74 | MEN1 (0.61) | MEN1KMT2AMAPTMAOADAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007403-B1 | 5,12-DIHYDROXY-1,2,3,4,6,11-HEXAHYDRO-2,6,11-TRIOXONAPHTHACENES AND THEIR SYNTHESIS | THE UNIVERSITY OF KANSAS (US) | 1982-11-24 | — | — | EP | claimed |
| US-20110015137-A1 | RECA INHIBITORS AND THEIR USES AS MICROBIAL INHIBITORS OR POTENTIATORS OF ANTIBIOTIC ACTIVITY | TRUSTEES OF BOSTON UNIVERSITY (US) | 2011-01-20 | — | — | US | disclosed |
| US-4739062-A | REACTING AN AROMATIC COMPOUND WITH DICARBOXYLIC ACID COMPOUND USING METAL HALIDE CATALYST | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1988-04-19 | — | — | US | disclosed |
| EP-0107486-B1 | AMINONAPHTHACENE DERIVATIVES AND THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015137-A1 | RECA INHIBITORS AND THEIR USES AS MICROBIAL INHIBITORS OR POTENTIATORS OF ANTIBIOTIC ACTIVITY | CGAS, RPIA, CLPP | MEN1 2527/4885KMT2A 4242/4885MAPT 3817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.