Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PTPRB | P23467 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1442737 | 0.89 | MMP8 (0.58) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL391783 | 0.87 | PPARG (0.61) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL8287672 | 0.87 | PPARG (0.61) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL7270701 | 0.86 | MMP8 (0.55) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL5713294 | 0.85 | MMP8 (0.68) | MMP8PPARGALDH1A1HSD17B10MDM2 | |
| SCHEMBL1259770 | 0.84 | MMP8 (0.54) | MMP8PPARGPPARDPPARAATM | |
| SCHEMBL7751974 | 0.83 | TSHR (0.47) | MMP8PPARGPPARAALDH1A1KMT2A | |
| SCHEMBL1586317 | 0.83 | MDM2 (0.61) | MMP8ALDH1A1MDM2NPC1RAB9A | |
| SCHEMBL5602964 | 0.83 | PNMT (0.49) | PPARGPPARAALDH1A1MDM2POLB | |
| SCHEMBL12344695 | 0.83 | MMP8 (0.53) | MMP8PPARGPPARDPPARAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005763-A1 | DIPEPTIDE-ANALOG-BASED METALLOENDOPEPTIDASE INHIBITORS AND METHODS OF USING SAME | THE SALK INSTITUTE BIOTECHNOLOGY/INDUSTRIAL ASSOCIATES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |