Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417797 | 0.79 | KMT2A (0.48) | ALDH1A1KDM4EHPGDCYP2C19TDP1 | |
| SCHEMBL27695892 | 0.78 | TDP1 (0.40) | ALDH1A1KDM4EHPGDCYP2C19TDP1 | |
| SCHEMBL9817222 | 0.73 | CYP2C19 (0.59) | ALDH1A1KDM4EHPGDCYP2C19TDP1 | |
| SCHEMBL7383122 | 0.72 | KMT2A (0.45) | ALDH1A1KDM4EHPGDCYP2C19MEN1 | |
| SCHEMBL3724640 | 0.71 | SMN1; SMN2 (0.47) | ALDH1A1KDM4EHPGDCYP2C19TDP1 | |
| SCHEMBL11450688 | 0.69 | CYP2C19 (0.40) | ALDH1A1KDM4EHPGDCYP2C19TDP1 | |
| SCHEMBL7114768 | 0.61 | SMN1; SMN2 (0.47) | ALDH1A1HPGDCYP2C19MEN1KMT2A | |
| SCHEMBL11450733 | 0.61 | KMT2A (0.50) | ALDH1A1HPGDCYP2C19TDP1MEN1 | |
| SCHEMBL29589309 | 0.60 | NOTUM (0.42) | ALDH1A1KDM4EHPGDCYP2C19TDP1 | |
| SCHEMBL2803342 | 0.60 | SLC9A1 (0.55) | ALDH1A1KDM4EHPGDCYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |