Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PARL | Q9H300 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417797 | 0.92 | KMT2A (0.48) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7383122 | 0.87 | KMT2A (0.45) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL7114768 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL9817222 | 0.83 | CYP2C19 (0.59) | SMN1; SMN2ALDH1A1HPGDKMT2ATDP1 | |
| SCHEMBL2803342 | 0.83 | SLC9A1 (0.55) | SMN1; SMN2ALDH1A1HPGDKMT2ACYP2C19 | |
| SCHEMBL11458575 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL11450733 | 0.80 | KMT2A (0.50) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL27695892 | 0.80 | TDP1 (0.40) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL11456500 | 0.80 | KMT2A (0.46) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL11450688 | 0.79 | CYP2C19 (0.40) | SMN1; SMN2ALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260137765-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2026-05-21 | — | — | US | disclosed |
| US-12527854-B2 | Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof | INSTITUT CURIE (FR) | 2026-01-20 | — | — | US | disclosed |
| US-20220233673-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF | INSTITUT CURIE (FR) | 2022-07-28 | — | — | US | disclosed |
| EP-2106263-B1 | WATER SOLUBLE REACTIVE DERIVATIVES OF CARBOXY POLYSACCHARIDES AND FIBRINOGEN CONJUGATES THEREOF | HEPACORE LTD (IL) | 2016-12-21 | — | — | EP | disclosed |
| US-20130084278-A1 | WATER SOLUBLE REACTIVE DERIVATIVES OF CARBOXY POLYSACCHARIDES AND FIBRINOGEN CONJUGATES THEREOF | HEPACORE LTD. (IL) | 2013-04-04 | — | — | US | disclosed |
| US-8329870-B2 | Water soluble reactive derivatives of carboxy polysaccharides and fibrinogen conjugates thereof | HEPACORE LTD. (IL) | 2012-12-11 | — | — | US | disclosed |
| US-20100086594-A1 | WATER SOLUBLE REACTIVE DERIVATIVES OF CARBOXY POLYSACCHARIDES AND FIBRINOGEN CONJUGATES THEREOF | HEPACORE LTD. (IL) | 2010-04-08 | — | — | US | disclosed |
| EP-2106263-A2 | WATER SOLUBLE REACTIVE DERIVATIVES OF CARBOXY POLYSACCHARIDES AND FIBRINOGEN CONJUGATES THEREOF | Hepacore Ltd. (IL) | 2009-10-07 | — | — | EP | disclosed |
| WO-2008081463-A2 | WATER SOLUBLE REACTIVE DERIVATIVES OF CARBOXY POLYSACCHARIDES AND FIBRINOGEN CONJUGATES THEREOF | HEPACORE LTD. (IL) | 2008-07-10 | — | — | WO | disclosed |
| US-RE32992-E | THERAPY FOR INFECTIOUS DISEASES CAUSED BY PATHOGENIC MICROORGANISMS | Fujisawa Pharaceutical Co., Ltd. (JP) | 1989-07-18 | — | — | US | disclosed |
| US-4427581-A | BACTERICIDES, FUNGICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| EP-0088386-A1 | New 1,4-diaminocyclitol derivatives, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-14 | — | — | EP | disclosed |
| US-4354966-A | Peptides, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| EP-0057412-A1 | Peptide, process for preparation thereof and use thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-08-11 | — | — | EP | disclosed |
| US-4311640-A | ANTIBIOTIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-01-19 | — | — | US | disclosed |
| EP-0027260-A2 | Peptides, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-22 | — | — | EP | disclosed |
| EP-0025842-A2 | Peptides, process for their preparation, their pharmaceutical compositions and their intermediates | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-01 | — | — | EP | disclosed |
| US-4242507-A | Sulfonic acid esters | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-12-30 | — | — | US | disclosed |
| US-4206156-A | ANTIMICROBIAL | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1980-06-03 | — | — | US | disclosed |
| US-4182758-A | BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12527854-B2 | Methods of producing Shiga toxin B-subunit (STxB) monomers and oligomers, and uses thereof | STXBP1, RNGTT, UPF1 | SMN1; SMN2 431/4885ALDH1A1 4838/4885HPGD 4708/4885 |
| US-20260137765-A1 | METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STXB) MONOMERS AND OLIGOMERS, AND USES THEREOF | STXBP1, HBB, UPF1 | SMN1; SMN2 526/4885ALDH1A1 4710/4885HPGD 4532/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.