Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.43 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7126488 | 0.77 | AKR1B1 (0.58) | GPR17AKR1B1PBRM1METERCC5 | |
| SCHEMBL9250840 | 0.77 | KDM4E (0.53) | METKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL28732562 | 0.77 | GPR17 (0.40) | GPR17AKR1B1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9038402 | 0.75 | GPR17 (0.61) | GPR17PBRM1ERCC5FEN1GRIN2D | |
| SCHEMBL31332450 | 0.75 | GPR17 (0.61) | GPR17PBRM1ERCC5FEN1GRIN2D | |
| SCHEMBL9272732 | 0.73 | GPR17 (0.60) | GPR17PBRM1ERCC5FEN1GRIN2D | |
| SCHEMBL29580629 | 0.71 | ALDH1A1 (0.69) | GPR17AKR1B1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL30064109 | 0.71 | PLA2G2A (0.57) | GPR17AKR1B1PLA2G2AGRIN2DGRIN3B | |
| SCHEMBL154385 | 0.71 | ALDH1A1 (0.69) | GPR17AKR1B1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6171799 | 0.71 | GPR17 (0.56) | GPR17AKR1B1PBRM1GRIN1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1052754-A | — | — | None | — | — | JP | disclosed |
| EP-0256128-B1 | INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-11-06 | — | — | EP | disclosed |
| JP-S6452754-A | DICHLOROINDOLINEACETIC ACID DERIVATIVE AND PRODUCTION THEREOF | NIPPON KAYAKU KK | 1989-02-28 | — | — | JP | disclosed |