SCHEMBL7126488

SCHEMBL7126488

O=C(O)Cc1c(Cl)[nH]c2cccc(Cl)c12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.58
GPR17 Q13304 1/20 0.57
PBRM1 Q86U86 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
ERCC5 P28715 1/20 0.43
FEN1 P39748 1/20 0.43
MCL1 Q07820 3/20 0.43
EGFR P00533 2/20 0.42
MET P08581 1/20 0.40
GRIN2D O15399 2/20 0.40
GRIN3B O60391 2/20 0.40
GRIN1 Q05586 2/20 0.40
GRIN2A Q12879 2/20 0.40
GRIN2B Q13224 2/20 0.40
GRIN2C Q14957 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9756207 0.82 AKR1B1 (0.46) AKR1B1GPR17KDM4EALDH1A1GAA
SCHEMBL6171799 0.80 GPR17 (0.56) AKR1B1GPR17PBRM1KDM4EALDH1A1
SCHEMBL9756296 0.77 GPR17 (0.50) AKR1B1GPR17PBRM1KDM4EALDH1A1
SCHEMBL29477149 0.77 KDM4E (0.66) AKR1B1KDM4EALDH1A1GAAMAPT
SCHEMBL4975424 0.77 KDM4E (0.66) AKR1B1KDM4EALDH1A1GAAMAPT
SCHEMBL109215 0.74 AKR1B1 (1.00) AKR1B1KDM4EGAAMAPT
SCHEMBL21392030 0.73 GPR17 (0.71) GPR17KDM4EALDH1A1GAAMAPT
SCHEMBL29062863 0.73 GPR17 (0.71) GPR17PBRM1KDM4EALDH1A1MCL1
Hydrochloric Acid SCHEMBL1374156 0.73 AKR1B1 (0.95) AKR1B1KDM4EGAAMAPT
SCHEMBL9364446 0.73 AKR1B1 (0.95) AKR1B1KDM4EGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6271032-B1 GROWING THE PLANT IN THE PRESENCE OF A GROWTH-ENHANCING FORMULATION COMPRISING 5-BROMOINDOLE-3-ACETIC ACID, ITS SALT, ESTER OR AMIDE DERIVATIVE INVITROGEN CORPORATION 2001-08-07 US claimed
US-20030083202-A1 Roots-inducing agent of plants and its treatment method KATAYAMA, MASATO (JP) 2003-05-01 US disclosed
CN-1401231-A Plant rooting promoter and treatment method thereof IND TECH COMPLEX INST (JP) 2003-03-12 CN disclosed
EP-0256128-B1 INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-11-06 EP disclosed
US-4806143-A Indoleacetic acid derivatives and application thereof as plant growth regulators NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-02-21 US disclosed
EP-0256128-A1 INDOLEACETIC ACID DERIVATIVES AND USE THEREOF AS PLANT GROWTH REGULATORS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1988-02-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030083202-A1 Roots-inducing agent of plants and its treatment method CROCC, PMAIP1, CYC1 AKR1B1 868/4885GPR17 3916/4885PBRM1 2338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.