Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | S100B | P04271 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CNR1 | P21554 | 7/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10336892 | 0.89 | S100B (0.43) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| SCHEMBL5595050 | 0.88 | S100B (0.46) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| Hydrochloric Acid SCHEMBL10632080 | 0.86 | S100B (0.45) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| Hydrochloric Acid SCHEMBL2141178 | 0.86 | S100B (0.45) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| Methanesulfonamide SCHEMBL10596161 | 0.85 | S100B (0.44) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| Sulfuric Acid SCHEMBL10605616 | 0.79 | S100B (0.43) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| SCHEMBL6849091 | 0.78 | S100B (0.46) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| SCHEMBL10713934 | 0.77 | CNR2 (0.40) | CNR2MEN1KMT2AS100BL3MBTL1 | |
| Sulfuric Acid SCHEMBL8632860 | 0.76 | S100B (0.42) | MEN1KMT2AS100BL3MBTL1MAPK1 | |
| SCHEMBL8633133 | 0.75 | CNR2 (0.40) | CNR2MEN1KMT2AS100BL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281000-B1 | MULTI-LAYER ANALYTICAL ELEMENT FOR CREATININE ANALYSIS | KONICA CORPORATION (JP) | 1991-10-16 | — | — | EP | disclosed |
| EP-0281000-A2 | Multi-layer analytical element for creatinine analysis | KONICA CORPORATION (JP) | 1988-09-07 | — | — | EP | disclosed |
| US-4732736-A | PEROXIDASE MATERIAL, HYDROGEN DONOR AND COUPLER | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1988-03-22 | — | — | US | disclosed |