Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PTPRA | P18433 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9756590 | 0.75 | HRH1 (0.42) | ALDH1A1MAPTSMN1; SMN2KMT2AALOX15 | |
| SCHEMBL11253725 | 0.69 | MAOA (0.43) | ALDH1A1MAPTPTPRASMN1; SMN2KMT2A | |
| Oxalic Acid SCHEMBL9231859 | 0.67 | PTPRA (0.53) | KDM4EALDH1A1CYP1A2CYP2C19CYP3A4 | |
| Oxalic Acid SCHEMBL27733515 | 0.67 | ALDH1A1 (0.58) | KDM4EALDH1A1CYP1A2CYP2C19CYP3A4 | |
| Oxalic Acid SCHEMBL27733516 | 0.67 | ALDH1A1 (0.58) | KDM4EALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9695439 | 0.66 | KDM4E (0.37) | KDM4EALDH1A1CYP1A2CYP2C19CYP2D6 | |
| Oxalic Acid SCHEMBL1156033 | 0.65 | ALDH1A1 (0.57) | KDM4EALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4612152 | 0.65 | HRH3 (0.46) | ALDH1A1CYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL28140567 | 0.65 | HRH3 (0.46) | ALDH1A1CYP1A2CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL28319826 | 0.65 | HRH1 (0.48) | ALDH1A1CYP1A2MAPTSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5025016-A | Mucolytic agents | LUDWIG HEUMANN & CO. GMBH (DE) | 1991-06-18 | — | — | US | claimed |
| US-5025016-A | Mucolytic agents | LUDWIG HEUMANN & CO. GMBH (DE) | 1991-06-18 | — | — | US | disclosed |