Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.45 |
| ▸ | GBA1 | P04062 | 4/20 | 0.45 |
| ▸ | CKS1B | P61024 | 2/20 | 0.45 |
| ▸ | SKP1 | P63208 | 2/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4-Methylbenzoic Acid SCHEMBL9671138 | 0.87 | GBA1 (0.48) | GPR119GBA1CKS1BSKP1SKP2 | |
| SCHEMBL9668922 | 0.86 | GPR119 (0.43) | GPR119GBA1CKS1BSKP1SKP2 | |
| SCHEMBL15921897 | 0.84 | CKS1B (0.55) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL10297496 | 0.84 | GPR119 (0.55) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL9756698 | 0.82 | GPR119 (0.43) | GPR119GBA1CKS1BSKP1SKP2 | |
| SCHEMBL9669980 | 0.81 | GBA1 (0.56) | GPR119GBA1CKS1BSKP1SKP2 | |
| SCHEMBL15921394 | 0.81 | MEN1 (0.54) | GPR119CKS1BSKP1SKP2ACHE | |
| SCHEMBL9756638 | 0.79 | GBA1 (0.49) | GPR119GBA1CKS1BSKP1SKP2 | |
| SCHEMBL9756677 | 0.78 | KMT2A (0.47) | GPR119GBA1CKS1BSKP1SKP2 | |
| SCHEMBL19385278 | 0.78 | TLR9 (0.73) | TLR9TLR7ALDH1A1KMT5AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011453-A2 | 5-OXYGENATED-2,4,6-TRIAMINOPYRIMIDINES | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | claimed |