Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 7/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756680 | 0.91 | MEN1 (0.55) | KMT2AMEN1SMN1; SMN2GBA1GPR119 | |
| SCHEMBL9756638 | 0.91 | GBA1 (0.49) | KMT2AMEN1GBA1GPR119ADORA2A | |
| SCHEMBL9756685 | 0.90 | SMN1; SMN2 (0.48) | KMT2AMEN1SMN1; SMN2GBA1GPR119 | |
| 4-Methylbenzoic Acid SCHEMBL9671138 | 0.84 | GBA1 (0.48) | KMT2AMEN1CYP2C19SMN1; SMN2GBA1 | |
| SCHEMBL9756679 | 0.84 | GBA1 (0.55) | GBA1CKS1BSKP1SKP2ACHE | |
| SCHEMBL9668922 | 0.82 | GPR119 (0.43) | GBA1GPR119ADORA2AADORA1CKS1B | |
| SCHEMBL9756696 | 0.78 | GPR119 (0.45) | GBA1GPR119ADORA2AADORA1CKS1B | |
| SCHEMBL9669962 | 0.74 | KMT5A (0.41) | GBA1GPR119ADORA2AADORA1CKS1B | |
| SCHEMBL15921897 | 0.74 | CKS1B (0.55) | KMT2AMEN1SMN1; SMN2GPR119ADORA2A | |
| SCHEMBL9756698 | 0.74 | GPR119 (0.43) | GBA1GPR119ADORA2AADORA1CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011453-A2 | 5-OXYGENATED-2,4,6-TRIAMINOPYRIMIDINES | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | claimed |