Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 5/20 | 0.49 |
| ▸ | CKS1B | P61024 | 2/20 | 0.49 |
| ▸ | SKP1 | P63208 | 2/20 | 0.49 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9756677 | 0.91 | KMT2A (0.47) | GBA1CKS1BSKP1SKP2ACHE | |
| SCHEMBL9756680 | 0.90 | MEN1 (0.55) | GBA1CKS1BSKP1SKP2ACHE | |
| SCHEMBL9756685 | 0.89 | SMN1; SMN2 (0.48) | GBA1TLR9TLR7ADORA2AADORA1 | |
| SCHEMBL9756679 | 0.87 | GBA1 (0.55) | GBA1CKS1BSKP1SKP2ACHE | |
| SCHEMBL9668922 | 0.83 | GPR119 (0.43) | GBA1CKS1BSKP1SKP2ACHE | |
| SCHEMBL9671054 | 0.80 | ALDH1A1 (0.46) | MEN1KMT2A | |
| SCHEMBL9756683 | 0.80 | CASP1 (0.43) | GBA1ACHEPTPN11MEN1KMT2A | |
| SCHEMBL9756696 | 0.79 | GPR119 (0.45) | GBA1CKS1BSKP1SKP2ACHE | |
| 4-Methylbenzoic Acid SCHEMBL9671138 | 0.77 | GBA1 (0.48) | GBA1CKS1BSKP1SKP2ACHE | |
| SCHEMBL27575995 | 0.75 | GBA1 (0.50) | GBA1CKS1BSKP1SKP2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991011453-A2 | 5-OXYGENATED-2,4,6-TRIAMINOPYRIMIDINES | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | claimed |