Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | NSD2 | O96028 | 1/20 | 0.67 |
| ▸ | ALPL | P05186 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | ALPI | P09923 | 1/20 | 0.67 |
| ▸ | ALPG | P10696 | 1/20 | 0.67 |
| ▸ | APEX1 | P27695 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | CASP6 | P55212 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1304499 | 0.81 | KDM4E (1.00) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL9756892 | 0.80 | LMNA (0.41) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL9756765 | 0.79 | LMNA (0.40) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL1224944 | 0.78 | ALDH1A1 (0.61) | ALDH1A1KDM4ETDP1GAALMNA | |
| SCHEMBL29556878 | 0.73 | KDM4E (0.74) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL9141827 | 0.73 | KDM4E (0.74) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL21638085 | 0.72 | LCK (0.57) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL31136177 | 0.72 | LCK (0.57) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL9756793 | 0.71 | LMNA (0.35) | ALDH1A1KDM4ETDP1BLMGAA | |
| SCHEMBL9756775 | 0.70 | LMNA (0.34) | ALDH1A1KDM4ETDP1BLMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077432-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-12-31 | — | — | US | claimed |
| US-5077432-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-12-31 | — | — | US | disclosed |
| EP-0438752-A1 | Monobactam hydrazides containing catechol sulfonic acid groups | E.R. SQUIBB & SONS, INC. (US) | 1991-07-31 | — | — | EP | disclosed |
| US-5030724-A | Monobactam hydrazides containing catechol sulfonic acid groups | E. R. SQUIBB & SONS, INC. (US) | 1991-07-09 | — | — | US | disclosed |