SCHEMBL1304499

SCHEMBL1304499

NNC(=O)c1cc(O)c(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 1.00
ALDH1A1 P00352 4/20 1.00
LMNA P02545 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
GAA P10253 3/20 1.00
MAPT P10636 2/20 1.00
BLM P54132 2/20 1.00
POLB P06746 2/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
NSD2 O96028 1/20 1.00
ALPL P05186 1/20 1.00
ALPI P09923 1/20 1.00
ALPG P10696 1/20 1.00
APEX1 P27695 1/20 1.00
HTT P42858 1/20 1.00
RECQL P46063 1/20 1.00
CASP6 P55212 1/20 1.00
TOP1 P11387 3/20 0.57
TOP2A P11388 3/20 0.57
TOP2B Q02880 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9141827 0.86 KDM4E (0.74) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL29556878 0.86 KDM4E (0.74) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL1893743 0.82 KDM4E (0.68) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL9756720 0.81 ALDH1A1 (0.67) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL28235986 0.80 KDM4E (0.67) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL12366809 0.80 KDM4E (0.66) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL13286830 0.79 KDM4E (0.65) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL131601 0.78 KDM4E (0.64) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL1303686 0.78 KDM4E (0.64) KDM4EALDH1A1LMNATDP1GAA
SCHEMBL21638084 0.78 KDM4E (0.64) KDM4EALDH1A1LMNATDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638993-A Polyaspartic acid derivative modified based on hydroxybenzoyl hydrazine, preparation method and application thereof 河南大学 2025-03-18 CN claimed
CN-119185637-A Multifunctional dressing for cornea epithelium repair and preparation method thereof 温州医科大学附属眼视光医院 2024-12-27 CN claimed
CN-116987015-A Gallic acid derivative containing urea structure and synthesis method and application thereof 江苏海洋大学 2023-11-03 CN claimed
CN-113788772-B Gallic acid derivative containing thiosemicarbazide, and synthesis method and application thereof 江苏海洋大学 2023-04-11 CN claimed
CN-113788772-A Gallic acid derivative containing thiosemicarbazide, and synthesis method and application thereof 江苏海洋大学 2021-12-14 CN claimed
CN-116987015-B Gallic acid derivative containing urea structure and synthesis method and application thereof 江苏海洋大学 2025-12-26 CN disclosed
US-12421257-B2 Compositions and methods for inhibiting group II intron RNA YALE UNIVERSITY (US) 2025-09-23 US disclosed
CN-119638993-A Polyaspartic acid derivative modified based on hydroxybenzoyl hydrazine, preparation method and application thereof 河南大学 2025-03-18 CN disclosed
CN-119185637-A Multifunctional dressing for cornea epithelium repair and preparation method thereof 温州医科大学附属眼视光医院 2024-12-27 CN disclosed
CN-114423766-B Pentane derivatives for the treatment of bacterial infections 丹诺医药(苏州)有限公司 2024-05-17 CN disclosed
US-20240018169-A1 COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA UNIV YALE (US) 2024-01-18 US disclosed
US-20240018169-A1 COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA UNIV YALE (US) 2024-01-18 US disclosed
WO-2019147894-A1 COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA YALE UNIVERSITY (US) 2019-08-01 WO disclosed
EP-2963011-B1 MOLECULAR CONJUGATE VENTANA MED SYST INC (US) 2018-05-09 EP disclosed
WO-2013059582-A2 SMALL MOLECULE INHIBITORS OF HISTONE DEACTEYLASES NUPOTENTIAL, INC. (US) 2013-04-25 WO disclosed
US-8053573-B2 Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof PIERRE FABRE DERMO-COSMETIQUE (FR) 2011-11-08 US disclosed
US-7994423-B2 Charge-transport materials, methods of fabrication thereof, and methods of use thereof GEORGIA TECH RESEARCH CORPORATION (US) 2011-08-09 US disclosed
US-20110009584-A1 Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety GEORGIA TECH RESEARCH CORPORATION (US) 2011-01-13 US disclosed
US-20090065057-A1 Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof GEORGIA TECH RESEARCH CORPORATION 2009-03-12 US disclosed
US-20080299055-A1 Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof PIERRE FABRE DERMO-COSMETIQUE (FR) 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12421257-B2 Compositions and methods for inhibiting group II intron RNA NSUN2, RBM22, RNGTT KDM4E 3981/4885ALDH1A1 2984/4885LMNA 606/4885
US-20080299055-A1 Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof POT1, TELO2, CLIC1 KDM4E 3517/4885ALDH1A1 581/4885LMNA 526/4885
US-20110009584-A1 Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety SLCO1B3, SLCO4C1, SLCO2B1 KDM4E 4711/4885ALDH1A1 1377/4885LMNA 3705/4885
US-20240018169-A1 COMPOSITIONS AND METHODS FOR INHIBITING GROUP II INTRON RNA NSUN2, RBM22, RNGTT KDM4E 3981/4885ALDH1A1 2984/4885LMNA 606/4885
US-20090065057-A1 Charge-Transport Materials, Methods of Fabrication Thereof, and Methods of Use Thereof SLC9A3, SLC18A2, SLC9A2 KDM4E 3683/4885ALDH1A1 3325/4885LMNA 609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.