Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28383522 | 1.00 | POLB (0.48) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL17537559 | 0.84 | POLB (0.49) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL51038 | 0.81 | ALDH1A1 (0.55) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL16205894 | 0.80 | ALDH1A1 (0.47) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL8824515 | 0.79 | CYP1A2 (0.58) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL8824516 | 0.79 | CYP1A2 (0.58) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL2541634 | 0.78 | ALDH1A1 (0.60) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL3202919 | 0.77 | ALDH1A1 (0.58) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL3202914 | 0.77 | ALDH1A1 (0.58) | POLBL3MBTL1TDP1KMT2AALDH1A1 | |
| SCHEMBL19220828 | 0.77 | ALDH1A1 (0.45) | POLBTDP1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5039684-A | Absorption when administered orally | VALEAS S. P. A. (IT) | 1991-08-13 | — | — | US | disclosed |
| EP-0384450-A1 | Tetrazole amide derivatives of heterocyclic alkenyl acids and their use as antiallergic substances | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1990-08-29 | — | — | EP | disclosed |