Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31425126 | 0.88 | ALDH1A1 (0.45) | ALDH1A1CYP1A2NPC1RAB9ACYP2C19 | |
| SCHEMBL51038 | 0.82 | ALDH1A1 (0.55) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL16205894 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP1A2NPC1RAB9ACYP2C19 | |
| SCHEMBL2541634 | 0.79 | ALDH1A1 (0.60) | ALDH1A1CYP1A2NPC1RAB9ACYP2C19 | |
| SCHEMBL9756802 | 0.77 | POLB (0.48) | ALDH1A1CYP1A2HTTTDP1POLB | |
| SCHEMBL28383522 | 0.77 | POLB (0.48) | ALDH1A1CYP1A2HTTTDP1POLB | |
| SCHEMBL29219910 | 0.76 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9ASMN1; SMN2TSHR | |
| SCHEMBL7717771 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7717768 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7717772 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170226075-A1 | Synthesis of Non-Ionic Surfactants From 5-Hydroxymethyl-2-Furfural, Furan-2,5-Dimethanol and Bis-2,5-Dihydroxymethyl-Tetrahydrofurans | ARCHER DANIELS MIDLAND CO (US) | 2017-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170226075-A1 | Synthesis of Non-Ionic Surfactants From 5-Hydroxymethyl-2-Furfural, Furan-2,5-Dimethanol and Bis-2,5-Dihydroxymethyl-Tetrahydrofurans | MTHFD2, DHFR, DHPS | ALDH1A1 2080/4885CYP1A2 1023/4885NPC1 3654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.