Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 8/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757489 | 0.85 | HTR7 (0.46) | KDM4EHSD17B10NPC1ALDH1A1TDP1 | |
| SCHEMBL9757308 | 0.80 | HTR7 (0.48) | KDM4EHSD17B10NPC1ALDH1A1TDP1 | |
| SCHEMBL9635395 | 0.79 | KDM4E (0.68) | KDM4EHSD17B10NPC1ALDH1A1TDP1 | |
| SCHEMBL5852592 | 0.79 | HDAC1 (0.71) | NPC1ALDH1A1HDAC3HDAC4HDAC1 | |
| SCHEMBL9757335 | 0.77 | HDAC3 (0.43) | KDM4EHSD17B10NPC1ALDH1A1TDP1 | |
| SCHEMBL9757630 | 0.76 | KDM4E (0.71) | KDM4EHSD17B10NPC1ALDH1A1TDP1 | |
| SCHEMBL7073791 | 0.74 | HDAC1 (0.63) | NPC1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9757401 | 0.71 | HTR1A (0.38) | KDM4EHSD17B10NPC1ALDH1A1TDP1 | |
| SCHEMBL9635285 | 0.70 | KDM4E (0.72) | KDM4EHSD17B10NPC1ALDH1A1TDP1 | |
| SCHEMBL14288509 | 0.66 | KDM4E (0.85) | KDM4EHSD17B10NPC1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036075-A | Serotonin antagonists | RHONE-POULENC SANTE (FR) | 1991-07-30 | — | — | US | disclosed |
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |