Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757010 | 0.93 | RAB9A (0.40) | RAB9AKDM4ENPC1LMNAMEN1 | |
| SCHEMBL9757288 | 0.92 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757240 | 0.90 | TEC (0.38) | RAB9AKDM4ENPC1MEN1MAPT | |
| SCHEMBL9757187 | 0.90 | TEC (0.38) | RAB9AKDM4ENPC1MEN1MAPT | |
| SCHEMBL9757114 | 0.86 | CYSLTR2 (0.46) | CYSLTR2CYSLTR1 | |
| SCHEMBL9756990 | 0.86 | CYSLTR1 (0.49) | CYSLTR2CYSLTR1 | |
| SCHEMBL9756995 | 0.83 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9756989 | 0.83 | CYSLTR1 (0.47) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757125 | 0.80 | CYSLTR1 (0.51) | CYSLTR2CYSLTR1 | |
| SCHEMBL9757222 | 0.80 | CYSLTR1 (0.35) | CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991019475-A2 | QUINOLINYL-BENZOHETEROBICYCLIC DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D¿4? | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-12-26 | — | — | WO | disclosed |