Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.57 |
| ▸ | HTR1A | P08908 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.57 |
| ▸ | HTR7 | P34969 | 5/20 | 0.57 |
| ▸ | HTR6 | P50406 | 5/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757336 | 0.90 | HTR1A (0.49) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL9757416 | 0.90 | DRD2 (0.61) | DRD2HTR1ASLC6A4HTR7HTR6 | |
| SCHEMBL9757403 | 0.89 | DRD2 (0.55) | DRD2 | |
| SCHEMBL9757367 | 0.88 | DRD2 (0.58) | DRD2 | |
| SCHEMBL9757300 | 0.84 | KDM4E (0.53) | DRD2 | |
| SCHEMBL9757463 | 0.81 | HTR7 (0.63) | DRD2HTR1AHTR7HTR6 | |
| SCHEMBL7048455 | 0.78 | — | — | |
| SCHEMBL9757450 | 0.78 | HTR7 (0.61) | HTR7 | |
| SCHEMBL9757375 | 0.76 | HTR7 (0.50) | DRD2HTR1AHTR7HTR6 | |
| SCHEMBL9757173 | 0.76 | HTR7 (0.64) | DRD2HTR1AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5036075-A | Serotonin antagonists | RHONE-POULENC SANTE (FR) | 1991-07-30 | — | — | US | disclosed |
| US-5021420-A | Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders | RHONE-POULENC SANTE (FR) | 1991-06-04 | — | — | US | disclosed |