Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243766 | 0.81 | L3MBTL3 (0.62) | MEN1KMT2AHDAC1ALDH1A1ADRA2A | |
| SCHEMBL8120677 | 0.81 | SIGMAR1 (0.52) | KCNH2HDAC1ALDH1A1ADRA2ASLC6A2 | |
| SCHEMBL9757217 | 0.79 | SIGMAR1 (0.50) | KCNH2HDAC1ALDH1A1ADRA2ASLC6A2 | |
| SCHEMBL23033079 | 0.77 | HDAC1 (0.50) | MEN1KMT2AHDAC1ALDH1A1KDM4E | |
| SCHEMBL9316466 | 0.77 | TMEM97 (0.49) | KCNH2HDAC1ALDH1A1ADRA2ASLC6A2 | |
| SCHEMBL23033083 | 0.77 | NAMPT (0.48) | MEN1KMT2AHDAC1ALDH1A1ADRA2A | |
| SCHEMBL8126590 | 0.76 | OPRK1 (0.54) | KMT2AKCNH2HDAC1ALDH1A1ADRA2A | |
| SCHEMBL1205833 | 0.76 | ACACB (0.55) | MEN1KMT2AKCNH2HDAC1ALDH1A1 | |
| SCHEMBL14626036 | 0.76 | CYP1A2 (0.54) | HDAC1ALDH1A1ADRA2ASLC6A2HTR2C | |
| SCHEMBL8122252 | 0.76 | HDAC1 (0.55) | MEN1KMT2AKCNH2HDAC1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026856-A | Bactericides | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1991-06-25 | — | — | US | disclosed |
| EP-0343560-A2 | Isoindoline derivative | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-11-29 | — | — | EP | disclosed |