SCHEMBL9757470

SCHEMBL9757470

CCNc1ccc2cn(-c3cc4c(cc3F)c(=O)c(C(=O)O)cn4CC)cc2c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 1/20 0.56
KDM4E B2RXH2 12/20 0.55
ALDH1A1 P00352 8/20 0.55
HPGD P15428 7/20 0.55
HTT P42858 7/20 0.55
LMNA P02545 5/20 0.55
HSD17B10 Q99714 3/20 0.55
TSHR P16473 2/20 0.55
BRD4 O60885 1/20 0.55
CYP2J2 P51589 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
USP2 O75604 1/20 0.54
TDP1 Q9NUW8 5/20 0.54
ATM Q13315 1/20 0.54
NPC1 O15118 1/20 0.54
POLB P06746 3/20 0.52
GAA P10253 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9757197 0.86 DRD3 (0.64) DRD3KDM4EALDH1A1HPGDHTT
SCHEMBL9757438 0.85 DRD3 (0.58) DRD3KDM4EALDH1A1HPGDHTT
SCHEMBL9757035 0.84 TDP1 (0.57) DRD3KDM4EALDH1A1HPGDHTT
SCHEMBL9757474 0.81 DRD3 (0.64) DRD3KDM4EALDH1A1HPGDHTT
Irloxacin SCHEMBL145215 0.78 DRD3 (0.67) DRD3KDM4EALDH1A1HPGDHTT
SCHEMBL22698659 0.78 HPGD (0.65) DRD3KDM4EALDH1A1HPGDHTT
Irloxacin SCHEMBL9743690 0.78 DRD3 (0.66) DRD3KDM4EALDH1A1HPGDHTT
Irloxacin SCHEMBL9743701 0.78 DRD3 (0.66) DRD3KDM4EALDH1A1HPGDHTT
SCHEMBL9700859 0.76 DRD3 (0.61) DRD3KDM4EALDH1A1HPGDHTT
SCHEMBL501895 0.75 DRD3 (0.68) DRD3KDM4EALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026856-A Bactericides WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
EP-0343560-A2 Isoindoline derivative WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed