Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817417 | 0.98 | NPC1 (0.46) | NPC1L3MBTL1GLATDP1PAM | |
| SCHEMBL1397184 | 0.98 | NPC1 (0.46) | NPC1L3MBTL1GLATDP1PAM | |
| SCHEMBL14838523 | 0.88 | HDAC2 (0.46) | NPC1L3MBTL1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL3239706 | 0.84 | NPC1 (0.44) | NPC1L3MBTL1GLATDP1PAM | |
| SCHEMBL11819176 | 0.84 | NPC1 (0.44) | NPC1L3MBTL1GLATDP1PAM | |
| SCHEMBL3870456 | 0.83 | ALDH1A1 (0.47) | NPC1L3MBTL1GLATDP1PAM | |
| SCHEMBL3866469 | 0.83 | HAO1 (0.47) | NPC1GLATDP1PAMLMNA | |
| SCHEMBL3870459 | 0.83 | ALDH1A1 (0.47) | NPC1L3MBTL1GLATDP1PAM | |
| SCHEMBL3866464 | 0.83 | HAO1 (0.47) | NPC1GLATDP1PAMLMNA | |
| SCHEMBL27717672 | 0.81 | PAM (0.46) | NPC1L3MBTL1GLATDP1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418254-A1 | TREATMENT OF SURFACES AND SURFACE LAYERS | PÜHRINGER, Josef, Dr. (SE) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989010386-A1 | TREATMENT OF SURFACES AND SURFACE LAYERS | PUEHRINGER JOSEF (SE) | 1989-11-02 | — | — | WO | disclosed |