SCHEMBL9757629

SCHEMBL9757629

O=S1(=O)c2cccc3cccc(c23)N1CCN1CC=C(c2ccccc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9757173 0.94 HTR7 (0.64) HTR7
SCHEMBL9757450 0.94 HTR7 (0.61) HTR7
SCHEMBL9757339 0.84 HTR1A (0.66) HTR7
SCHEMBL9757207 0.84
SCHEMBL9757463 0.84 HTR7 (0.63) HTR7
SCHEMBL9757570 0.84
SCHEMBL9757366 0.83 HTR7 (0.49) HTR7
Hydrochloric Acid SCHEMBL9757178 0.83 HTR7 (0.48) HTR7
SCHEMBL9757300 0.82 KDM4E (0.53)
SCHEMBL9871315 0.82 HTR7 (0.55) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5036075-A Serotonin antagonists RHONE-POULENC SANTE (FR) 1991-07-30 US disclosed