SCHEMBL9871315

SCHEMBL9871315

COc1ccc(C2=CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)cc1

nearest known ligand 0.79

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9757450 0.88 HTR7 (0.61) HTR7
SCHEMBL9757207 0.87
SCHEMBL9757339 0.87 HTR1A (0.66) HTR7
SCHEMBL9757570 0.87
SCHEMBL9757173 0.86 HTR7 (0.64) HTR7
SCHEMBL9757463 0.85 HTR7 (0.63) HTR7
SCHEMBL9757629 0.82 HTR7 (0.54) HTR7
SCHEMBL7048455 0.81
SCHEMBL9757375 0.79 HTR7 (0.50) HTR7
SCHEMBL9757366 0.79 HTR7 (0.49) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021420-A Antiserotonine agents; central nervous system, gastroin-testinal and cardiovascular disorders RHONE-POULENC SANTE (FR) 1991-06-04 US disclosed