Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850282 | 0.85 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9700024 | 0.78 | CA12 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11296801 | 0.77 | L3MBTL1 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL17929073 | 0.76 | TSHR (0.39) | TDP1RXRARXRBRXRGKDM4E | |
| SCHEMBL15457980 | 0.76 | KDM4E (0.51) | TDP1L3MBTL1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL10535275 | 0.75 | ALDH1A1 (0.55) | TDP1L3MBTL1PLAUKDM4EALDH1A1 | |
| SCHEMBL426616 | 0.74 | CA12 (0.77) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7152724 | 0.74 | ELANE (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9515089 | 0.74 | CA12 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28026161 | 0.74 | CA12 (0.46) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049685-A | Nuclear substituted salicylic acids and their salts | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-09-17 | — | — | US | disclosed |
| EP-0370389-A2 | Nuclear substituted salicylic acids and their salts | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1990-05-30 | — | — | EP | disclosed |