Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 12/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29580634 | 0.83 | LMNA (0.50) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL2050108 | 0.83 | LMNA (0.50) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL9324920 | 0.75 | ESR1 (0.49) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL9757645 | 0.72 | LMNA (0.41) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL30281291 | 0.70 | PDK2 (0.50) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL19039047 | 0.70 | PDK2 (0.50) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL2884823 | 0.70 | ESR1 (0.50) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL23996970 | 0.69 | PDK2 (0.45) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL5968629 | 0.69 | KDM4E (0.45) | PDK2LMNAMAPTKDM4EMEN1 | |
| SCHEMBL813078 | 0.68 | THRB (0.52) | PDK2LMNAMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055616-A | 9,9-bis(3-alkyl-4-amino-5-isopropylphenyl) fluorene; for use in gas separation membranes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-10-08 | — | — | US | disclosed |