SCHEMBL2050108

SCHEMBL2050108

CC(C)c1cc(C2(c3cc(C(C)C)c(N)c(C(C)C)c3)c3ccccc3-c3ccccc32)cc(C(C)C)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
OPRK1 P41145 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
PDK2 Q15119 4/20 0.36
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
ALOX15 P16050 1/20 0.34
CYP2C19 P33261 1/20 0.34
PAX8 Q06710 1/20 0.34
HIF1A Q16665 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29580634 1.00 LMNA (0.50) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL9324920 0.91 ESR1 (0.49) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL9757645 0.87 LMNA (0.41) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL5968629 0.84 KDM4E (0.45) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL9757874 0.83 PDK2 (0.40) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL2884823 0.83 ESR1 (0.50) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL9757903 0.82 LMNA (0.38) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL3884293 0.78 SMN1; SMN2 (0.50) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL6138105 0.77 SMN1; SMN2 (0.67) LMNAMAPTMEN1KMT2AKDM4E
SCHEMBL20573241 0.77 LMNA (0.49) LMNAMAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200140722-A1 CURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2020-05-07 US claimed
EP-2900726-B1 RESIN COMPOSITION AND COMPOSITE STRUCTURE CONTAINING RESIN HEXCEL COMPOSITES LTD (GB) 2020-04-08 EP claimed
EP-3562856-A1 CURABLE COMPOSITIONS 3M Innovative Properties Company (US) 2019-11-06 EP claimed
WO-2018125692-A1 CURABLE COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-07-05 WO claimed
EP-2900726-A2 RESIN COMPOSITION AND COMPOSITE STRUCTURE CONTAINING RESIN Hexcel Composites Limited (GB) 2015-08-05 EP claimed
US-20150210847-A1 RESIN COMPOSITION AND COMPOSITE STRUCTURE CONTAINING RESIN HEXCEL COMPOSITES LIMITED (GB) 2015-07-30 US claimed
EP-0851887-B1 EPOXY RESIN COMPOSITIONS, PREPREGS, CURED COMPOSITES, AND METHODS OF MAKING THE SAME MINNESOTA MINING & MFG (US) 2003-04-23 EP claimed
US-6054221-A A FLUORENE AMINE CURATIVE PARTIALLY MELT DISSOLVED AND PARTIALLY DISPERSED AS A SOLID IN AN AROMATIC POLYEPOXIDE; PREPREGS HAVING TACK WITH GOOD SHELF LIFE PROPERTIES; NON-DIFFUSING; COMPARABLE GLASS TRANSITION TEMPERATURES 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-04-25 US claimed
US-5728755-A EXHIBIT TACK AND GOOD SHELF LIFE, LITTLE RESIN MIGRATION AND GLASS TRANSITION TEMPERATURE SIMILAR TO THOSE CURED NEAT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-17 US claimed
US-4684678-A POLYEPOXIDES OF HIGH GLASS TRANSITION TEMPERATURE AND DUCTILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-08-04 US claimed
US-11370908-B2 Curable compositions and related methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-06-28 US disclosed
US-20220080553-A1 RAPID CURING BONDED ABRASIVE ARTICLE PRECURSOR 3M INNOVATIVE PROPERTIES CO (US) 2022-03-17 US disclosed
US-20220001514-A1 ABRASIVE ARTICLE WITH MICROPARTICLE-COATED ABRASIVE GRAINS 3M INNOVATIVE PROPERTIES COMPANY 2022-01-06 US disclosed
US-20210292545-A1 PREPREG TORAY INDUSTRIES, INC. (JP) 2021-09-23 US disclosed
US-11078358-B2 Curable composition including epoxy resin and curable solid filler 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-08-03 US disclosed
US-5369192-A Aromatic epoxide with bis(aminophenyl)fluorene compound curing agent MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1994-11-29 US disclosed
US-5055616-A 9,9-bis(3-alkyl-4-amino-5-isopropylphenyl) fluorene; for use in gas separation membranes AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-10-08 US disclosed
EP-0203828-B1 EPOXY RESIN CURING AGENT, CURING PROCESS AND COMPOSITION CONTAINING IT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-03-28 EP disclosed
US-4684678-A POLYEPOXIDES OF HIGH GLASS TRANSITION TEMPERATURE AND DUCTILITY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-08-04 US disclosed
EP-0203828-A1 Epoxy resin curing agent, curing process and composition containing it MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-12-03 EP disclosed