Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9757645 | 0.84 | LMNA (0.41) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL2050108 | 0.82 | LMNA (0.50) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL29580634 | 0.82 | LMNA (0.50) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL9324920 | 0.77 | ESR1 (0.49) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL15815775 | 0.76 | GABRA1 (0.49) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL7723158 | 0.75 | GABRA1 (0.43) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL5968924 | 0.74 | MEN1 (0.45) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL6949064 | 0.73 | ESR1 (0.51) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL29632697 | 0.73 | KDM4E (0.46) | LMNAKDM4EMEN1MAPTOPRK1 | |
| SCHEMBL20226272 | 0.72 | MAPT (0.36) | LMNAKDM4EMEN1MAPTOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055616-A | 9,9-bis(3-alkyl-4-amino-5-isopropylphenyl) fluorene; for use in gas separation membranes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-10-08 | — | — | US | disclosed |