Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759148 | 0.96 | MAPT (0.36) | MAPTPOLBHPGDCYP1A2LMNA | |
| SCHEMBL9757935 | 0.96 | PKM (0.36) | MAPTPOLBHPGDALDH1A1CYP1A2 | |
| SCHEMBL9757950 | 0.96 | MAPT (0.38) | MAPTPOLBHPGDCYP1A2LMNA | |
| SCHEMBL9759139 | 0.95 | NAAA (0.37) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL9759088 | 0.95 | NAAA (0.37) | MAPTALDH1A1LMNAMAPK1HTT | |
| SCHEMBL9758502 | 0.94 | ALDH1A1 (0.35) | MAPTHPGDALDH1A1LMNAHTT | |
| SCHEMBL9758550 | 0.93 | NAAA (0.37) | MAPTCYP1A2MAPK1HTTNAAA | |
| SCHEMBL9758891 | 0.93 | PKM (0.36) | MAPTPOLBHPGDCYP1A2LMNA | |
| SCHEMBL9759387 | 0.92 | NAAA (0.38) | ALDH1A1LMNAHTTNAAATSHR | |
| SCHEMBL9759152 | 0.92 | NAAA (0.38) | ALDH1A1LMNAHTTNAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985583-A | Liquid Crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-15 | — | — | US | disclosed |