Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9758727 | 0.88 | DRD2 (0.43) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL9759328 | 0.83 | PSEN1 (0.42) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL8891880 | 0.83 | DRD2 (0.51) | CYP1A2DRD2DRD3DRD4HTR1D | |
| SCHEMBL9758631 | 0.83 | MTNR1A (0.41) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL8893102 | 0.82 | MTNR1A (0.62) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL9183762 | 0.81 | DRD2 (0.58) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL9759575 | 0.81 | MTNR1A (0.43) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| Hydrochloric Acid SCHEMBL7935647 | 0.81 | MTNR1A (0.60) | MTNR1AMTNR1BCYP1A2MAPTCYP2C9 | |
| SCHEMBL8631318 | 0.79 | DRD2 (0.60) | DRD2DRD3DRD4HTR1D | |
| SCHEMBL8630806 | 0.79 | DRD2 (0.60) | DRD2DRD3DRD4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047422-A | Treating A Disorder Of The Central Nervous System, Cardiovascular System Or Intestinal Tract | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4968679-A | DISORDERS OF CENTRAL NERVOUS SYSTEM, CARDIOVASCULAR SYSTEM OR INTESTINAL TRACT | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| US-4873262-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, CARDIIOVASCULAR SYSTEM OR INTESTINAL TRACT | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-10 | — | — | US | disclosed |