Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331583 | 0.89 | LMNA (0.37) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9759838 | 0.85 | BCHE (0.41) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9334139 | 0.82 | KMT2A (0.40) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9758879 | 0.81 | HTR1A (0.39) | MAPTLMNANOX1MAPK1TDP1 | |
| Fumaric Acid SCHEMBL9759348 | 0.79 | BCHE (0.40) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9332058 | 0.78 | HDAC3 (0.45) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9759784 | 0.78 | DRD3 (0.34) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9759075 | 0.78 | DRD3 (0.34) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9332105 | 0.78 | KMT2A (0.45) | MAPTLMNANOX1MAPK1TDP1 | |
| SCHEMBL9759044 | 0.78 | LMNA (0.42) | MAPTLMNAMAPK1TDP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |