Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9331571 | 1.00 | PTGS1 (0.46) | PTGS1ACHELMNAPGRCHRM2 | |
| SCHEMBL9331568 | 1.00 | PTGS1 (0.46) | PTGS1ACHELMNAPGRCHRM2 | |
| SCHEMBL9759590 | 0.99 | PTGS1 (0.47) | PTGS1ACHELMNAPGRCHRM2 | |
| SCHEMBL9331494 | 0.99 | PTGS1 (0.47) | PTGS1ACHELMNAPGRCHRM2 | |
| Hydrochloric Acid SCHEMBL9334936 | 0.98 | PTGS1 (0.46) | PTGS1ACHELMNAPGRCHRM2 | |
| Hydrochloric Acid SCHEMBL9331475 | 0.98 | PTGS1 (0.46) | PTGS1ACHELMNAPGRCHRM2 | |
| SCHEMBL9759036 | 0.88 | LMNA (0.44) | PTGS1ACHELMNAPGRCHRM2 | |
| SCHEMBL9758776 | 0.87 | ALDH1A1 (0.48) | PTGS1ACHELMNAPGRCHRM2 | |
| SCHEMBL10385689 | 0.87 | ACHE (0.41) | PTGS1ACHELMNAPGRCHRM2 | |
| SCHEMBL9758956 | 0.87 | ALDH1A1 (0.48) | PTGS1ACHELMNAPGRCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049669-A | Also diuretics | RHONE-POULENC SANTE (FR) | 1991-09-17 | — | — | US | disclosed |
| US-4985419-A | Analgesics, Diuretics | RHONE-POULENC SANTE (FR) | 1991-01-15 | — | — | US | disclosed |