Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.33 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759455 | 0.78 | HDAC6 (0.52) | KAT2BALDH1A1HDAC6MAPTPTGER4 | |
| SCHEMBL9759870 | 0.78 | ALDH1A1 (0.39) | ALDH1A1CASP1MAPTLMNAHTT | |
| SCHEMBL9759837 | 0.78 | HDAC6 (0.40) | KAT2BGUCY1A1GUCY1B1HDAC1HDAC6 | |
| SCHEMBL4450289 | 0.76 | NQO2 (0.42) | NQO2KAT2BGUCY1A1GUCY1B1ALDH1A1 | |
| SCHEMBL9759498 | 0.76 | CYP3A4 (0.34) | KAT2BALDH1A1HDAC6MAPTPTGER4 | |
| SCHEMBL9759574 | 0.75 | NQO2 (0.41) | NQO2KAT2BGUCY1A1GUCY1B1ALDH1A1 | |
| SCHEMBL7136500 | 0.75 | KAT2B (0.57) | NQO2KAT2BGUCY1A1GUCY1B1ALDH1A1 | |
| SCHEMBL28030459 | 0.75 | TLR8 (0.46) | NQO2KAT2BGUCY1A1GUCY1B1ALDH1A1 | |
| SCHEMBL13015196 | 0.73 | PTGER4 (0.47) | NQO2ALDH1A1CASP1MAPTLMNA | |
| SCHEMBL11442397 | 0.71 | ALDH1A1 (0.45) | NQO2KAT2BGUCY1A1GUCY1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | claimed |
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | disclosed |