Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759574 | 0.87 | NQO2 (0.41) | NQO2KAT2BALDH1A1LMNAGUCY1A1 | |
| SCHEMBL6449056 | 0.78 | MAPT (0.58) | ALDH1A1LMNAMAPTGAAHTR1A | |
| SCHEMBL28030459 | 0.78 | TLR8 (0.46) | NQO2KAT2BALDH1A1GUCY1A1GUCY1B1 | |
| SCHEMBL7136500 | 0.78 | KAT2B (0.57) | NQO2KAT2BALDH1A1GUCY1A1GUCY1B1 | |
| SCHEMBL4450288 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTCASP1GAA | |
| SCHEMBL13015196 | 0.76 | PTGER4 (0.47) | NQO2ALDH1A1LMNAMAPTCASP1 | |
| SCHEMBL9759565 | 0.76 | MAPT (0.44) | ALDH1A1MAPTGAA | |
| SCHEMBL9759577 | 0.76 | NQO2 (0.39) | NQO2KAT2BALDH1A1LMNAGUCY1A1 | |
| SCHEMBL959868 | 0.75 | MTNR1A (0.43) | ALDH1A1LMNAMAPTGAAHDAC1 | |
| SCHEMBL11442397 | 0.74 | ALDH1A1 (0.45) | NQO2KAT2BALDH1A1LMNAGUCY1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | claimed |
| EP-1697150-B1 | CROSSLINKABLE ELASTOMERIC COMPOSITION AND TIRE FOR VEHICLE WHEELS COMPRISING THE SAME | PIRELLI & C SPA (IT) | 2009-04-01 | — | — | EP | disclosed |
| US-20070185239-A1 | Crosslinkable elastomeric composition and tire for vehicle wheels comprising the same | PIRELLI & C. S.P.A. (IT) | 2007-08-09 | — | — | US | disclosed |
| EP-1697150-A1 | CROSSLINKABLE ELASTOMERIC COMPOSITION AND TIRE FOR VEHICLE WHEELS COMPRISING THE SAME | Pirelli & C. S.p.A. (IT) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058615-A1 | CROSSLINKABLE ELASTOMERIC COMPOSITION AND TIRE FOR VEHICLE WHEELS COMPRISING THE SAME | PIRELLI & C. S.P.A. (IT) | 2005-06-30 | — | — | WO | disclosed |
| EP-1339539-B9 | PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS | PIRELLI (IT) | 2005-06-15 | — | — | EP | disclosed |
| EP-1339539-B1 | PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS | PIRELLI (IT) | 2005-01-19 | — | — | EP | disclosed |
| US-20040094252-A1 | Process for manufacturing, moulding and curing tyres for vehicles wheels | PIRELLI PNEUMATICI S.P.A. (IT) | 2004-05-20 | — | — | US | disclosed |