Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759577 | 0.78 | NQO2 (0.39) | ALDH1A1HTTCASP1MAPTLMNA | |
| SCHEMBL4450288 | 0.76 | ALDH1A1 (0.42) | ALDH1A1HTTTDP1CASP1HRH3 | |
| SCHEMBL9759837 | 0.76 | HDAC6 (0.40) | HTTTDP1LMNACYP3A4ALOX15 | |
| SCHEMBL9759455 | 0.76 | HDAC6 (0.52) | ALDH1A1MAPTCYP3A4KDM4EGAA | |
| SCHEMBL825579 | 0.75 | MAPT (0.52) | ALDH1A1HRH3MAPTNPC1RAB9A | |
| SCHEMBL9759867 | 0.75 | ALDH1A1 (0.41) | ALDH1A1HTTTDP1CASP1HRH3 | |
| SCHEMBL8159092 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HTTTDP1CASP1MAPT | |
| SCHEMBL2455817 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HTTTDP1CASP1MAPT | |
| SCHEMBL9759498 | 0.73 | CYP3A4 (0.34) | ALDH1A1HTTMAPTCYP3A4TSHR | |
| SCHEMBL29262271 | 0.72 | ABL1 (0.53) | ALDH1A1HTTTDP1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | claimed |
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | disclosed |