SCHEMBL9759853

SCHEMBL9759853

CCCCC1CCC(C2CCC(C)(C(=O)OC)CC2)CC1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.40
MAPT P10636 2/20 0.38
CYP1A2 P05177 2/20 0.37
POLB P06746 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 2/20 0.36
LMNA P02545 1/20 0.36
MAPK1 P28482 1/20 0.36
GAA P10253 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TP53 P04637 1/20 0.34
TLR4 O00206 2/20 0.33
PKM P14618 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9758581 0.96 CYP1A2 (0.39) NAAAMAPTCYP1A2POLBHPGD
SCHEMBL9758005 0.91 TLR4 (0.40) NAAAMAPTLMNACYP2C9TLR4
SCHEMBL9758894 0.87 MAPT (0.38) NAAAMAPTCYP1A2POLBHPGD
SCHEMBL9757950 0.87 MAPT (0.38) NAAAMAPTCYP1A2POLBHPGD
SCHEMBL9757982 0.86 MAPT (0.37) NAAAMAPTCYP1A2POLBHPGD
SCHEMBL9758891 0.85 PKM (0.36) NAAAMAPTCYP1A2POLBHPGD
SCHEMBL9759148 0.85 MAPT (0.36) NAAAMAPTCYP1A2POLBHPGD
SCHEMBL9759088 0.83 NAAA (0.37) NAAAMAPTHTTLMNAMAPK1
SCHEMBL9759139 0.83 NAAA (0.37) NAAAMAPTHTTLMNAMAPK1
SCHEMBL9757828 0.83 TP53 (0.38) NAAAMAPTCYP1A2POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4985583-A Liquid Crystals MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-01-15 US disclosed