Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12286918 | 0.87 | HSD17B10 (0.52) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11689608 | 0.85 | CASP3 (0.39) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10724396 | 0.82 | HSD17B10 (0.47) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6851983 | 0.80 | HSD17B10 (0.50) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL13982720 | 0.80 | ALDH1A1 (0.46) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11444322 | 0.80 | GPR35 (0.47) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11684809 | 0.79 | HSD17B10 (0.48) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL2775290 | 0.78 | CASP3 (0.51) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL27781078 | 0.78 | HSD17B10 (0.48) | HSD17B10TDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10494262 | 0.77 | HSD17B10 (0.42) | HSD17B10TDP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293073-B1 | CHROMAN-6-SULPHONYL DERIVATIVES | Wendstone Chemicals P.L.C. (GB) | 1991-09-18 | — | — | EP | claimed |