Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.39 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.39 |
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | DHFR | P00374 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.35 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL978050 | 0.81 | HTR7 (0.34) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL978140 | 0.77 | SLC29A1 (0.38) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL25215379 | 0.76 | HTR7 (0.43) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL28718276 | 0.75 | SMPD1 (0.44) | — | |
| SCHEMBL25249190 | 0.72 | HTR7 (0.45) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL25244877 | 0.71 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL25292470 | 0.71 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL25293732 | 0.71 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL25288209 | 0.71 | HTR7 (0.46) | HTR7HTR1ADRD2HTR2AHTR6 | |
| SCHEMBL975684 | 0.69 | SLC29A1 (0.34) | MAPTMAPK1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289898-B1 | Melamine-functional organosilicon compound and making method | SHINETSU CHEMICAL CO (JP) | 2017-05-03 | — | — | EP | disclosed |
| US-8263766-B2 | Melamine-functional organosilicon compound and making method | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-09-11 | — | — | US | disclosed |
| EP-2289898-A1 | Melamine-Functional organosilicon compound and making method | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-03-02 | — | — | EP | disclosed |
| US-20110003989-A1 | MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003989-A1 | MELAMINE-FUNCTIONAL ORGANOSILICON COMPOUND AND MAKING METHOD | MEN1, MSH6, PRMT6 | HTR7 590/4885HTR1A 1403/4885DRD2 1961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.