SCHEMBL9760120

SCHEMBL9760120

C=C(C=O)C(=O)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.46
TDP1 Q9NUW8 3/20 0.41
ATM Q13315 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALOX15 P16050 2/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40
ALDH1A1 P00352 2/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 4/20 0.39
RAD51 Q06609 1/20 0.39
MEN1 O00255 1/20 0.38
MAPT P10636 3/20 0.38
KDM4E B2RXH2 1/20 0.38
NSD2 O96028 1/20 0.38
ALOX5 P09917 1/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11426974 0.84 ELANE (0.46) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL6658962 0.83 ELANE (0.52) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL544811 0.82 ELANE (0.45) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL9760126 0.81 TDP1 (0.36) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL29286252 0.79 ELANE (0.50) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL5704145 0.79 ELANE (0.42) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL5132602 0.79 ELANE (0.52) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL8246907 0.78 ELANE (0.41) ELANETDP1ATML3MBTL1ALOX15
Diphenyl Ethanedioat SCHEMBL43364 0.78 TDP1 (0.54) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL8238681 0.77 ELANE (0.44) ELANETDP1ATML3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101633654-B Ring carbonic ester monomer containing acrylate class functional group as well as preparation and application thereof UNIV SOOCHOW 2013-10-09 CN disclosed
CN-101633654-A Ring carbonic ester monomer containing acrylate class functional group as well as preparation and application thereof UNIV SUZHOU 2010-01-27 CN disclosed
US-5049634-A Derivatized and/or crosslinked products from acetal- and aldehyde-containing polysaccharide graft polymers NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1991-09-17 US disclosed