Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11426974 | 0.82 | ELANE (0.46) | ELANETHRBKMT2AMEN1TDP1 | |
| SCHEMBL9760120 | 0.78 | ELANE (0.46) | ELANEKMT2AMEN1TDP1ATM | |
| SCHEMBL14510762 | 0.78 | THRB (0.36) | ELANETHRBKMT2AMEN1TDP1 | |
| SCHEMBL9909074 | 0.77 | LMNA (0.41) | KMT2ATDP1L3MBTL1HSD17B10PARP10 | |
| SCHEMBL544811 | 0.77 | ELANE (0.45) | ELANETHRBKMT2AMEN1TDP1 | |
| SCHEMBL8251160 | 0.76 | HSP90AA1 (0.40) | KMT2AMEN1TDP1ATMMAOB | |
| SCHEMBL8238681 | 0.75 | ELANE (0.44) | ELANETHRBTDP1ATML3MBTL1 | |
| Butadiene SCHEMBL11803057 | 0.75 | ELANE (0.65) | ELANETHRBKMT2ATDP1ATM | |
| SCHEMBL20548109 | 0.74 | HDAC3 (0.41) | KMT2AMEN1TDP1MAOBMAPT | |
| SCHEMBL5704145 | 0.74 | ELANE (0.42) | ELANEKMT2AMEN1TDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996439-A1 | $g(b)-ALKOXYACRYLATES AGAINST MALARIA | F. HOFFMANN-LA ROCHE AG (CH) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999002150-A1 | β-ALKOXYACRYLATES AGAINST MALARIA | F. HOFFMANN-LA ROCHE AG (CH) | 1999-01-21 | — | — | WO | disclosed |