Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760120 | 0.81 | ELANE (0.46) | TDP1ALDH1A1MAPK1ALOX15LMNA | |
| SCHEMBL632410 | 0.77 | ELANE (0.50) | TDP1ALDH1A1ALOX15LMNAF2 | |
| Methacrylic Acid SCHEMBL2939572 | 0.74 | ELANE (0.47) | TDP1ALDH1A1ALOX15ELANEKMT2A | |
| SCHEMBL32679139 | 0.74 | CA4 (0.41) | ALDH1A1ELANEKMT2ASMN1; SMN2GAA | |
| SCHEMBL32679140 | 0.74 | CA4 (0.41) | ALDH1A1ELANEKMT2ASMN1; SMN2GAA | |
| SCHEMBL1054428 | 0.74 | HCAR2 (0.43) | ALDH1A1ALOX15THRBLMNAF2 | |
| SCHEMBL3156584 | 0.74 | ALDH1A1 (0.39) | TDP1ALDH1A1ALOX15THRBTGM2 | |
| SCHEMBL134191 | 0.73 | MAPT (0.40) | TDP1ALDH1A1ALOX15ELANEKMT2A | |
| SCHEMBL28965920 | 0.73 | LMNA (0.42) | ALDH1A1LMNACYP2D6ELANEKMT2A | |
| SCHEMBL7259561 | 0.72 | MEN1 (0.53) | ALDH1A1LMNAKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049634-A | Derivatized and/or crosslinked products from acetal- and aldehyde-containing polysaccharide graft polymers | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 1991-09-17 | — | — | US | disclosed |