SCHEMBL544811

SCHEMBL544811

C=C(C=S)C(=O)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.45
TDP1 Q9NUW8 2/20 0.40
ATM Q13315 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
ALOX15 P16050 2/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 2/20 0.39
RAD51 Q06609 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 2/20 0.37
KDM4E B2RXH2 1/20 0.37
NSD2 O96028 1/20 0.37
ALOX5 P09917 1/20 0.37
CYP19A1 P11511 1/20 0.35
THRB P10828 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1412681 0.90 FABP7 (0.44) ELANETDP1HSD17B10MEN1KMT2A
SCHEMBL11426974 0.82 ELANE (0.46) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL9760120 0.82 ELANE (0.46) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL4828994 0.81 CYP11B1 (0.41) ELANEHPGDALDH1A1MEN1KMT2A
SCHEMBL29286252 0.78 ELANE (0.50) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL5704145 0.78 ELANE (0.42) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL1412687 0.78 MAPT (0.47) TDP1ATML3MBTL1ALOX15HSD17B10
SCHEMBL6658962 0.77 ELANE (0.52) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL5132602 0.77 ELANE (0.52) ELANETDP1ATML3MBTL1ALOX15
SCHEMBL8246907 0.77 ELANE (0.41) ELANETDP1ATML3MBTL1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080146729-A1 Aqueous ink composition and method of manufacturing the same SEIKO EPSON CORPORATION 2008-06-19 US claimed
US-7374799-B2 Radiation sensitive composition, microlens, process for forming microlens and use of the microlens JSR CORPORATION (JP) 2008-05-20 US claimed
US-20050004261-A1 Aqueous ink composition and method of manufacturing the same SEIKO EPSON CORPORATION 2005-01-06 US claimed
EP-4378928-A1 NAPHTHALENE DITHIOL AND DERIVATIVE THEREOF, AND PRODUCTION METHODS AND USES FOR SAME SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) 2024-06-05 EP disclosed
US-20230399563-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC ARTICLE AND EYEGLASSES HOYA LENS THAILAND LTD. (TH) 2023-12-14 US disclosed
US-20230359068-A1 OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND HOYA LENS THAILAND LTD. (TH) 2023-11-09 US disclosed
EP-4206799-A1 OPTICAL ARTICLE, EYEGLASSES AND PHOTOCHROMIC COMPOUND Hoya Lens Thailand Ltd. (TH) 2023-07-05 EP disclosed
EP-4067353-A1 PHOTOCHROMIC COMPOUND, PHOTOCHROMIC ARTICLE AND EYEGLASSES Hoya Lens Thailand Ltd. (TH) 2022-10-05 EP disclosed
US-9159356-B2 Non-resonant two-photon absorption recording material, non-resonant polymer two-photon absorption optical information recording medium, and recording/reproducing method FUJIFILM CORPORATION (JP) 2015-10-13 US disclosed
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD FUJIFILM CORPORATION (JP) 2014-03-20 US disclosed
US-8110617-B2 Aqueous ink composition and method of manufacturing the same SEIKO EPSON CORPORATION (JP) 2012-02-07 US disclosed
US-5214116-A Acrylic polymers with thioester group, lenses, optical fibers, optical recording media TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1993-05-25 US disclosed
US-4931521-A Optical materials composed of resin from thioacrylat esters NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1990-06-05 US disclosed
US-4791183-A 1,2-DIHALOETHYL STYRENES ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-12-13 US disclosed
US-4732887-A RESIN IN VOIDS FOR CHROMATOGRAPHY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1988-03-22 US disclosed
EP-0060472-B1 A METHOD FOR SEPARATING T CELLS FROM LEUKOCYTES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1986-12-17 EP disclosed
US-4430445-A POLYAMIDINE HOHO- AND COPOLYMERS; OXIDATION RESISTANCE; METAL EXTRACTION; POLYEPOXIDE CURING AGENTS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-02-07 US disclosed
US-4425237-A Method for separating T cells from leukocytes ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1984-01-10 US disclosed
EP-0060472-A2 A method for separating T cells from leukocytes Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-09-22 EP disclosed
US-4202775-A CROSSLINKABLE ETHYLENICALLY UNSATURATED POROUS COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140078878-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL, NON-RESONANT POLYMER TWO-PHOTON ABSORPTION OPTICAL INFORMATION RECORDING MEDIUM, AND RECORDING/REPRODUCING METHOD PUF60, PARG, FHIT ELANE 4613/4885TDP1 2709/4885ATM 3724/4885
US-20230359068-A1 OPTICAL ARTICLE, SPECTACLES, AND PHOTOCHROMIC COMPOUND GRK1, TCOF1, ARPC1B ELANE 4567/4885TDP1 4672/4885ATM 843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.