Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 9/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760363 | 0.80 | KDM4E (0.49) | KDM4EALDH1A1HTTHPGDPLA2G2A | |
| SCHEMBL8768671 | 0.77 | KDM4E (0.66) | KDM4EALDH1A1HTTHPGDPLA2G2A | |
| SCHEMBL9760954 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HTTHPGDPLA2G2A | |
| SCHEMBL10780306 | 0.75 | KDM4E (0.62) | KDM4EALDH1A1HTTHPGDPLA2G2A | |
| SCHEMBL10780298 | 0.75 | KDM4E (0.43) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL9760348 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1HPGDMAPTLMNA | |
| SCHEMBL4013841 | 0.71 | KDM4E (0.51) | KDM4EALDH1A1HPGDMAPTMAPK1 | |
| SCHEMBL10774157 | 0.70 | GAA (0.51) | KDM4EALDH1A1HTTHPGDPLA2G2A | |
| SCHEMBL8822991 | 0.69 | KMT2A (0.66) | KDM4EALDH1A1HTTHPGDPLA2G2A | |
| SCHEMBL10365894 | 0.66 | ALDH1A1 (0.63) | KDM4EALDH1A1HPGDMAPTHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997940-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-05 | — | — | US | claimed |
| US-5021591-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4997940-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4992091-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | disclosed |