Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10780298 | 0.88 | KDM4E (0.43) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL19436700 | 0.82 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL9792974 | 0.82 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL9760377 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL28701963 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL10774291 | 0.75 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL9761046 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL9760147 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL17351816 | 0.71 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10HPGDTP53 | |
| SCHEMBL9792968 | 0.71 | ALDH1A1 (0.53) | KDM4EALDH1A1HSD17B10HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997940-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-05 | — | — | US | claimed |
| US-5021591-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-06-04 | — | — | US | disclosed |
| US-4997940-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-03-05 | — | — | US | disclosed |
| US-4992091-A | Herbicides | THE DOW CHEMICAL COMPANY (US) | 1991-02-12 | — | — | US | disclosed |