Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 6/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.41 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720997 | 0.81 | PTGS2 (0.46) | CYP19A1MAOBBCHECYP1B1SNCA | |
| SCHEMBL7720996 | 0.81 | PTGS2 (0.46) | CYP19A1MAOBBCHECYP1B1SNCA | |
| SCHEMBL9760328 | 0.78 | MAPK1 (0.47) | MAOBMAOALMNAMAPTALDH1A1 | |
| SCHEMBL7655049 | 0.78 | BCHE (0.50) | CYP19A1MAOBBCHECYP1B1SNCA | |
| SCHEMBL10416822 | 0.78 | MAPK1 (0.43) | LMNAMAPTALDH1A1POLBMAPK1 | |
| SCHEMBL7651789 | 0.76 | SNCA (0.44) | CYP19A1MAOBBCHECYP1B1SNCA | |
| SCHEMBL8386280 | 0.74 | MEN1 (0.44) | CYP19A1MAOBBCHECYP1B1SNCA | |
| SCHEMBL8471201 | 0.70 | ALDH1A1 (0.51) | MAOBMAOALMNAMAPTALDH1A1 | |
| SCHEMBL9134846 | 0.69 | TDP1 (0.78) | MAOBBCHECYP1B1MAOAMAPT | |
| SCHEMBL9134841 | 0.69 | TDP1 (0.78) | MAOBBCHECYP1B1MAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |