Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | ATM | Q13315 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712444 | 0.88 | NR4A1 (0.53) | NR4A1MAPTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL9712528 | 0.85 | AKR1C3 (0.50) | AKR1C3NR4A1GAAMAPTALDH1A1 | |
| SCHEMBL1331831 | 0.83 | AKR1C3 (0.57) | AKR1C3NR4A1GAAMAPTALDH1A1 | |
| SCHEMBL64069 | 0.83 | AKR1C3 (0.57) | AKR1C3NR4A1GAAMAPTALDH1A1 | |
| SCHEMBL10657458 | 0.82 | AKR1C3 (0.52) | AKR1C3NR4A1GAAMAPTALDH1A1 | |
| SCHEMBL9760328 | 0.81 | MAPK1 (0.47) | GAAMAPTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL525385 | 0.79 | AKR1C3 (0.48) | AKR1C3NR4A1GAAMAPTALDH1A1 | |
| SCHEMBL9249733 | 0.79 | AKR1C3 (0.48) | AKR1C3GAAMAPTALDH1A1L3MBTL1 | |
| SCHEMBL30403796 | 0.78 | TSHR (0.64) | AKR1C3NR4A1GAAMAPTALDH1A1 | |
| SCHEMBL334531 | 0.78 | TSHR (0.64) | AKR1C3NR4A1GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2056897-B1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES B V (NL) | 2009-12-30 | — | — | EP | claimed |
| US-20090258053-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEEVICES BV (NL) | 2009-10-15 | — | — | US | claimed |
| EP-2056897-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | Blue Medical Devices B.V. (NL) | 2009-05-13 | — | — | EP | claimed |
| US-20080050413-A1 | Medical stent provided with a combination of melatonin and paclitaxel | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | US | claimed |
| WO-2008023038-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | WO | claimed |
| US-6632940-B1 | Glycosidic coupling between donor and acceptor in presence of Bronsted or Lewis acid to form glucopyranose-D- glucopyranose | LABORATOIRES GOEMAR (FR) | 2003-10-14 | — | — | US | claimed |
| US-9610427-B2 | Narrow profile composition-releasing expandable medical balloon catheter | WELLINQ MEDICAL B.V. (NL) | 2017-04-04 | — | — | US | disclosed |
| US-20160213895-A1 | NARROW PROFILE COMPOSITION-RELEASING EXPANDABLE MEDICAL BALLOON CATHETER | BLUE MEDICAL DEVICES B.V. (NL) | 2016-07-28 | — | — | US | disclosed |
| EP-2501431-A1 | NARROW PROFILE COMPOSITION-RELEASING EXPANDABLE MEDICAL BALLOON CATHETER | Blue Medical Devices B.V. (NL) | 2012-09-26 | — | — | EP | disclosed |
| US-20120232640-A1 | NARROW PROFILE COMPOSITION-RELEASING EXPANDABLE MEDICAL BALLOON CATHETER | BLUE MEDICAL DEVICES BV (NL) | 2012-09-13 | — | — | US | disclosed |
| WO-2011061295-A1 | NARROW PROFILE COMPOSITION-RELEASING EXPANDABLE MEDICAL BALLOON CATHETER | BLUE MEDICAL DEVICES BV (NL) | 2011-05-26 | — | — | WO | disclosed |
| EP-2056897-B1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES B V (NL) | 2009-12-30 | — | — | EP | disclosed |
| US-20090258053-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEEVICES BV (NL) | 2009-10-15 | — | — | US | disclosed |
| EP-2056897-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | Blue Medical Devices B.V. (NL) | 2009-05-13 | — | — | EP | disclosed |
| US-20080050413-A1 | Medical stent provided with a combination of melatonin and paclitaxel | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | US | disclosed |
| WO-2008023038-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258053-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | MTNR1B, MTNR1A, MYLK | AKR1C3 4167/4885NR4A1 2018/4885GAA 3758/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.